![]() Both the oral and IV formulations of the drug combination are well tolerated. Further, oral netupitant/palonosetron was found to be superior to palonosetron and non-inferior to aprepitant plus granisetron in preventing CINV in individual trials. In clinical trials, (fos)netupitant/palonosetron plus dexamethasone was associated with high complete response rates (no emesis and no rescue medication) in the acute, delayed and overall phases in patients receiving highly or moderately emetogenic chemotherapy, with efficacy maintained over multiple cycles. Administered as a single dose, (fos)netupitant/palonosetron (in combination with dexamethasone) is indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) in adults. doi: 10.1007/s0052-1.Netupitant/palonosetron (NEPA Akynzeo ®), available in oral and intravenous (IV) formulations, is a fixed-dose combination of the neurokinin 1 (NK1) receptor antagonist netupitant (or the prodrug, fosnetupitant, in the IV formulation) and the second-generation serotonin 3 (5-HT 3) receptor antagonist palonosetron. 2016 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following moderately emetogenic chemotherapy. NCCN Clinical Practice Guildelines in Oncology (NCCN Guidelines®): antiemesis (version 1.2021). 2016 Updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following high emetic risk chemotherapy. Overview of chemotherapy-induced nausea and vomiting and evidence-based therapies. The Author(s), under exclusive licence to Springer Nature Switzerland AG.Īdel N. In conclusion, netupitant/palonosetron is a simple, convenient and effective drug combination for the prevention of acute and delayed CINV in patients receiving chemotherapy that has a moderate to high potential to cause nausea and vomiting. Both the oral and intravenous formulations of the drug combination are well tolerated. In clinical trials, high proportions of patients who received netupitant/palonosetron (used in combination with the corticosteroid dexamethasone) prior to chemotherapy reported no vomiting, no requirement for rescue medication, and no significant nausea in the 5 days post chemotherapy. Approved for use in the prevention of acute and delayed CINV in adults, netupitant/palonosetron is given orally or via intravenous infusion as a single dose prior to chemotherapy. Netupitant/palonosetron (NEPA Akynzeo ®) is a fixed-dose combination of two drugs (netupitant, a neurokinin 1 receptor antagonist and palonosetron, a serotonin 3 receptor antagonist) which target two different signalling pathways involved in the induction of vomiting. The fixed-dose combination is concordant with guideline recommendations and provides a simple and convenient option for prophylaxis against acute and delayed CINV in patients receiving highly or moderately emetogenic chemotherapy.Ĭhemotherapy-induced nausea and vomiting (CINV) is a common problem during cancer treatment. Netupitant/palonosetron (NEPA Akynzeo ®), available in oral and intravenous (IV) formulations, is a fixed-dose combination of the neurokinin 1 (NK1) receptor antagonist netupitant (or the prodrug, fosnetupitant, in the IV formulation) and the second-generation serotonin 3 (5-HT 3) receptor antagonist palonosetron.
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![]() “Salt is good, but if the salt has lost its saltiness, how will you make it salty again? Have salt in yourselves, and be at peace with one another.” – Mark 9:50 “May the God of endurance and encouragement grant you to live in such harmony with one another, in accord with Christ Jesus.” -Romans 15:5 Never be wise in your own sight.” – Romans 12:16 Do not be haughty, but associate with the lowly. He didn’t look for fights or quarrels, and when the Pharisees tested Him, He always answered with love. He didn’t provoke others, nor did He let himself get provoked. And when offense arises, seek to make peace by either apologizing or forgiving. You can live at peace with others by not saying hateful comments or speeches towards them, not looking for their trouble, provoking them, etc. We love one another by living at peace with them. “ …Clothe yourselves, all of you, with humility toward one another, for “God opposes the proud but gives grace to the humble.” – 1 Peter 5:5 “ Do nothing from selfish ambition or conceit, but in humility count others more significant than yourselves.” – Philippians 2:3 “ submitting to one another out of reverence for Christ.” – Ephesians 5:21 ![]() He never exalted Himself, He listened to others’ concern, and always thought of them more. Jesus humbled Himself to become human and die on the cross (Philippians 2:8), He was humble towards His earthly parents and obeyed them (Luke 2:51). C.S Lewis said, “ humility is not thinking less of you, but thinking of you less.” You can act humbly towards others by listening to them, not blaming them for your mistakes, accepting their critique or reproach, receiving their help, considering them, showing interest in them, and not thinking or acting like you are better or more important than them. Loving others means putting them above yourself. “And let us consider how to stir up one another to love and good works, not neglecting to meet together, as is the habit of some, but encouraging one another” – Hebrews 10:2 4-25 “But exhort one another every day, as long as it is called “today,” that none of you may be hardened by the deceitfulness of sin.” – Hebrews 3:13 “Therefore encourage one another and build one another up, just as you are doing.” – 1 Thessalonians 5:11 ![]() “Therefore encourage one another with these words. He still encourages and comforts us today, and He wants us to comfort others as well (2 Corinthians 1:3-5). Jesus exemplified it many times with His disciples, as illustrated in John 14:1, John 14:27, John 16:33. A word of encouragement can make such a vast difference in others’ lives, and we have an unlimited supply of it. You help them go through their trials and keep moving forward. When you encourage someone, you give them courage, support, and hope. *All Scriptures are taken from the English Standard Version unless noted otherwise.* Here are a few things you can do to love others, and also how Jesus did these things for us. On the contrary, He left us a detailed guide with practical ways we can love one another as He loves us. Thankfully God didn’t make it a mystery or guesswork. The question now is, what actions demonstrate love for one another? I previously did a word study on love and learned that biblical love is mostly action. Loving others is obviously a big deal it’s one of the greatest commandments, and it’s at the core of Christianity. This commandment appears in several other places in the New Testament such as in John 13:34, John 15:12, John 15:17, Romans 13:8, 1 Thessalonians 3:12, 2 Thessalonians 1:3, 1 Peter 1:22, 1 John 3:11, 1 John 3:23, 1 John 4:7, 1 John 4:11-12, and 2 John 5. ![]() He said in John 13:34 “ A new commandment I give to you, that you love one another: just as I have loved you, you also are to love one another.” Jesus commanded us to love one another as He loves us. ![]() Serve garnished with fresh thyme and rosemary sprigs. Add the chops to the pan and simmer, turning occasionally, until just heated through, 1 to 2 minutes. Stir in the remaining 1 tablespoon butter, vinegar and parsley. Add pork chops to a large skillet coated with oil, and place. Close tightly and turn gently to coat well. ![]() Place pork chops in a zip-top bag and pour marinade over the top. Whisk in the cream and simmer to bring the sauce together, about 1 minute. Instructions In a small bowl, stir together apple cider, apple cider vinegar, soy sauce, salt, garlic, and thyme. Add the stock, bring to a simmer and cook until slightly thickened, 2 to 3 minutes. Whisk in the cider and bring to a simmer. Sprinkle in the flour and stir to make a paste. Add the garlic, rosemary and thyme and cook until sizzling, about 30 seconds. Add 1 tablespoon of the butter and place over medium heat. (If the chops are browning too quickly or the pan drippings start to burn, lower the heat.) Remove to a plate.įor the sauce: Discard all but 1 tablespoon fat from the pan. When the oil is hot, add the chops (work in batches if necessary do not crowd the pan) and cook, turning occasionally, until they are golden brown and cooked through, 13 to 14 minutes. Pour the marinade over pork chops, squeeze out excess air and seal the bag. Then place in a large resealable plastic bag. Heat a large skillet over medium heat and add the olive oil. Pork Chop Marinade In a medium-sized bowl, mix together the soy sauce, brown sugar, ketchup, apple cider vinegar, garlic, and olive oil. Put the bag in a shallow container so it can lay flat and refrigerate for 30 minutes and up to 4 hours.ĭrain the chops, rinse and pat dry. Put the pork chops in a large resealable plastic bag and pour in the brine. Remove from the heat and pour in the cold cider. Bring to a simmer over medium heat and stir to dissolve the sugar and salt, about 1 minute. For the brine: combine the salt, brown sugar, peppercorns, coriander, mustard seeds, allspice berries, bay leaves, thyme and 1 1/2 cups water in a small saucepan. Want to see a demonstration? Watch the last video tutorial in this article.
![]() Standard delivery: Delivery will be done within one (1) to three (3) days from the receipt of your order.Įxpress same-day delivery: Delivery will be done within the same day for orders placed before 4pm. I recommend using a primer before applying your foundation, simply because it creates a barrier between the foundation and your skin which is always a good idea.Įventhough the foundation lasts beautifully, I recommend using a setting powder and setting spray for longer-lasting results.We are proposing 3 types of shipping methods: I found that because the Luminous Silk Foundation is so creamy and silky, it applies really easily and therefore does not need a sponge.Įverything absorbs perfectly with a brush or even your fingers. Like most foundations, you can apply it with whichever method you like best. It also works really well for sensitive skin. ![]() This is because it doesn’t look thick or heavy on the skin, and it doesn’t exaggerate any lines or blemishes. The Armani Luminous Silk Foundation ticks all the boxes! It is particularly good for mature and ageing skin as well as dry skin. A natural-looking foundation is an absolute must for me and the Luminous Silk is like Photoshop in a bottle. I have a combination to dry skin type that has a lot of open pores that need covering and this foundation aces it! Another thing you should know about me and my foundation is that I hate it when foundations settle into my lines. What Skin Type is the Armani Luminous Silk for? At the end of the day, my foundation looks exactly the same as when I applied it in the morning. I wear my foundation for about 12 – 14 hours at a time and it doesn’t move. The foundation has a satin finish to it which gives the skin a beautiful radiant glow throughout the day that doesn’t looks shiny or oily. I went to my local Fenwicks and got a small sample that has actually lasted me a week now since all you need is a small amount each time.Īll I can say is that after giving the Luminous Silk Foundation a fair amount of time to get to know, I absolutely love it. Giorgio Armani is one of those brands that’s worth trying out before spending the full amount because it is on the pricey side. I love this because instead of buying an expensive foundation and then regretting it, you can ask for a sample and then use it for a few days to see if it works for you. Perhaps I’m late in discovering this secret, but most makeup shops when asked will give you a sample to try out. ![]() Giorgio Armani aimed to get the foundation to feel like the softest silk fabric, and I can confirm, it definitely feels like silk.Īlso made with glycerin which helps give the skin hydration throughout the day. The foundation was inspired by charmeuse silk which apparently is the fabric of emperors. Each foundation colour comes in warm, neutral and cool to match every skin tone. The darks also look like a nice colour range, although I don’t think the darkest is dark enough for some. The colour range for light skin is really good, it has a shade for even the palest skin. Giorgio Armani Luminous Silk Foundation comes in 40 impressive shades. This unique formula gives the foundation the flawless finish that we all love! Shades and Ingredients of the Luminous Silk The foundation is formulated with an exclusive unique “Micro–fil™ technology which allows buildable color pigments to lay flat on your skin for seamless blending and layering, improving skin’s texture, and blurring imperfection”. Normal, Dry, Combination, Sensitive, Oily ![]() A white blaze, chest, tail tip, or feet is characteristic. Nova Scotia Duck Tolling Retriever Older Dogs for Sale Displaying Notices From: If the region is not displayed in the dropdown list above, then we have no breeders in our database for that particular region. A longer coat is not appropriate for a working dog, although the tail feathering should be long, adding to the emphasis of the wagging tail. ![]() Because they were bred to work in icy waters, they have a water-repelling double coat of medium length. If you are looking to buy a NSDR you would need to pay anything from 350 to over 600 for a well-bred pedigree puppy. Their powerful yet compact build enables them to rush around tirelessly, leaping and retrieving with tail always wagging. We consider ourselves ambassadors and advocates for the breed and are always here to help educate anyone interested in learning more!įor more information on this wonderful breed click HERE for the CKC breed standard (in adobe pdf format, aprx 10k).Because Tollers run as much as they swim when "tolling," they are smaller and more agile than most other retrievers. If you have any questions please feel free to contact us by email or phone. We hope you enjoy your visit here with us. Saltydog Kennel's on YouTube Waiting for Wigeon's due date around May 18th, 2023. Families will be notified within 2 weeks according longest waiting. It is also why we carefully select the girls and boys we use in our breed program. SALTYDOG NOVA SCOTIA DUCK TOLLING RETRIEVERS NOVA SCOTIA DUCK TOLLING RETRIEVERS, Nova Scotia, Canada Puppies arrived Cyanne has 7 Girls and 2 Boys. We also do yearly blood work to check out thyroid levels and titer levels among other things. To ensure that we breed the best possible furbabies we do health testing including CERF, OFA and Optigen. On our website, you can find information. The NSDTR Club of Canada recognizes those listed as members in good standing but neither endorses nor guarantees their services. We are the family Vriend and we are the owners of our Nova Scotia Duck Tolling Retrievers Lynn, Hugo, Evi and Raya. Our dogs are raw fed and minimally vaccinated. Toller Breeder Directory Nova Scotia Duck Tolling Retriever Club of Canada (NSDTRCC) Breeder Directory Toller Breeder The NSDTR Club of Canada’s Breeder Directory is paid advertising. Any less, and you will never have the perfect dog. This is why we take breeding these wonderful dogs so seriously and are one hundred percent committed to not just adding to the breed but improving it. Tollwest Kennels - Alberta Nova Scotia Duck Tolling Retriever Breeders Want to list your puppies for sale Post a classified today About Tollwest Kennels At Tollwest, we believe Tollers should 'have it all'.health, temperament, soundness, working ability and breed type. We believe in breeding and raising dynamic all-around dogs. This adaptably and flexibility of mind and body is the cornerstone of our breed program. RedMoon Tollers is a small kennel located in Northern California. Nova Scotia Duck Tolling Retriever At Forest Cove Tollers our breeding program focuses on excellent structure, strong working ability and great temperaments. To get a healthy dog, never buy a puppy from an irresponsible breeder, puppy mill, or pet store. After all a Dog Is A Lifetime Commitment and a great Toller has to be able to adapt to you their family and not the other way around. Expect a wait of six months to a year or more for a puppy. This means Tollers which are equally happy in the field or on your couch. ![]() Dogs which enhance your happiness and bring joy to all those around them. ![]() This is why we here at Nopper are committed to producing family friendly Nova Scotia Duck Tolling Retrievers which are joy to live with and live with for a long time. While some have a lot to say, they all are great listeners and enjoy nothing more than just BEING with their people. They are steadfast and loyal, intelligent and easily trainable, precious and playful, and while they are reserved with strangers once they know you, they are your friend for life! These dogs love nothing more than to play fetch or go for a walk with their people. In our opinion, Tollers are probably one of the best "all purpose" dogs. Our Nova Scotia Duck Tolling Retriever Wall. Welcome to Nopper Permanently Register CKC Kennel where our commitment to Tollers is paramount. Shop for nova scotia duck tolling retriever wall art from the worlds greatest living artists and iconic brands. Susan Nepomucenos Nova Scotia Duck Tolling Retrievers. ![]()
Lock operator has final authority on the suitability of a craft for lockage. Please follow the directions of the lock operator when using the locks or operating in the vicinity of the locks. Most closures are planned months or years in advance, but emergencies may require closing locks to traffic at any time. ![]() Lock closures can be as short as 1 day or as long as 30 days. If you plan to travel by boat on one of these waterway systems, we recommend that you check for scheduled lock closures before you leave. The district maintains 22 locks on 4 different waterway systems including the Black Warrior & Tombigbee Rivers, the Tennessee-Tombigbee Waterway, the Alabama River, and the Apalachicola-Chattahoochee-Flint Rivers. Army Corps of Engineers, Mobile District, is the primary point of contact when requesting to “lock through”. If you are experiencing consistent errors, we're here to help.As the operator and maintainer of locks on several major waterways in the southeast, the U.S. Technical Issues - Registration and Access Troubleshooting Guides Note: User registrations and user role requests will need to be approved by your Supervisor and Security Officer. Please ensure entries for Supervisor and Security Officer are correct in your AMPS profile prior to submitting a role request. For Step 10 of the AMPS User Role Request, enter application name and select Search. This document will guide you through the process in requesting a role in one of the following applications: HMIRS NextGen, DD Form 1685, MEDALS, QDB, iGIRDER, LOLA Classic, WebFLIS, or E-Cat. Read the "Complete and Submit a Role Request" document and apply for a role.If you already have an AMPS account, please proceed to step 3. This document in the User Guides and Job Aids will guide you through the process in obtaining an AMPS account. Read the "AMPS User Guide" document and apply for an AMPS account.A CAC or PIV certificate is required for access. Follow these steps to obtain access to the above applications. Other methods of applications will no longer be accepted. Logistics On-Line Access Classic (LOLA Classic)Īccounts are handled via AMPS.Interactive Government Industry Data Edit Review (iGIRDER).Military Engineering Data Asset Locator System (MEDALS).Hazardous Materials Information Resource System (HMIRS) NextGen. ![]() Web Federal Logistics Information System (WebFLIS).Hazardous Material Management System-Performance Oriented Packaging (HMMS-POP) application customers should reference the HMMS-POP instructions for HMMS-POP-specific directions.įollow the three steps below before trying to access the following DLA applications for the first time: Reutilization, Transfer or Donation (RTD) application customers should reference the RTD AMPS instructions for RTD-specific directions. Learn how to register for an account (PDF) If you cannot authenticate your identity with a smart card, you can still obtain an AMPS account to request roles relevant to the business you want to conduct with either of these organizations. Access to any requested application is provided through the application itself or through the portal provided by the sponsoring organization. Having an account in AMPS enables you to request an application role, submit and track the request, and receive a notification when the request is granted. ![]() When a role is approved, the user has access to the application resource What AMPS is NOT.ĪMPS is NOT a portal to any application. Application users, both internal (civilians, military, and contractors) and external (vendors, public), can have AMPS accounts that enable them to submit requests for these roles. Access is based on the approval of your request for one or more application roles. The Account Management and Provisioning System (AMPS) can set up your access to computer application resources or provide information to a provisioner for manual setup. This phet simulation of a neural cell membrane using a sodium potassium pump will help you visualize this form of active transport. In this section you will work your way through an animation of cellular transport and answer some questions to activate the model. Use your outline from EXPLAIN to be sure you have information on all cellular transport modes.Ī crash course video on all modes of cellular transportĪ video with a different approach to learning the various types of transport from Paul Anderson Crash Course Biology makes analogies and quickly moves through the material, while Bozeman Science speaks with a more intent tone and moves more slowly, providing many authentic examples. In this section you will need to choose which video best fits your learning style. This does not involve the direct usage of energy by atp in the process, but the movement of the membrane fusing and rearranging requires an input of energy by the cell. Passive and Active transport In this reading, focus on the the sodium potassium pump information for active transport.Įndocytosis and Exocytosis in this reading you will learn about the way cells ingest or expel extra large particles. Passive Transport- This is a very thorough and informative section about the specifics of passive transport. Use your outline from above to be sure you have information on all cellular transport modes. In this section you will need to read several passages to experience all the modes of cellular transport. This will help your brain organize to remember the content. Active Transport and Passive Transport will be your topic, with Roman numerals and the types of transport as letters. ![]() Let’s see what you know! Assign the following cellular transportation methods to either Active Transport AT or Passive Transport PT.Ĭheck your answers and then use the correct answers to organize the information in an outline form. ![]() If no energy or ATP is required to move material into or out of a cell, it is called passive transport. If it takes energy to move material into or out a cell, it is call Active Transport. The key concept to learn about cellular transport is to categorize the way material moves into and out of a cell by energy requirements! Remember ATP? ATP is cellular energy. ![]() ![]() StandardsīIO.A.2.2.3 Compare and contrast the structure and function of carbohydrates, lipids, proteins, and nucleic acids in organisms.īIO.A.4.2.1 Explain how organisms maintain homeostasis (e.g., thermoregulation, water regulation, oxygen regulation).īIO.A.4.1.2 Compare and contrast the mechanisms that transport materials across the plasma membrane (i.e., passive transport - diffusion, osmosis, facilitated diffusion active transport - pumps, endocytosis, exocytosis).īIO.A.4.1.1 Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell. Your participation in a simple virtual lab wil help you quickly observe results to aid in understanding concentration gradients and the movement of material across a cellular membrane. There are many activities in the Engage section, each with a specific concentration in a type of transport. In this seminar you will inventory your knowledge of cellular transport and learn to organize the transport types based on energy requirements. ![]() If you prefer not to have cookies stored within your web-browser, please adjust your browser settings accordingly. For more detailed information regarding the use of cookies on this website, please see our "Privacy Policy". By using this website, you consent to the use of cookies. ![]() Our website uses cookies to help improve your visit. Supported OS: Windows 11, Windows 10, Windows 8.1, Windows 7 RAM (Memory): 2 GB. ![]() Supported OS: Windows 11, Windows 10, Windows 8.We want you to have the best possible experience while using our service. 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